As of Aug 2026, Unbox Health has lab tested and rated 3 products in the Vitamin D3+K2 category.
We buy every product from the open market, with no brand involvement. Every product is tested at up to 3 NABL-accredited labs. Products are then rated D to A+, based on the following dimensions: their label accuracy, their toxicity and their nutritional profile (in the case of food products). All lab reports are published.
Read the full methodology for how we rate Vitamin D3+K2 here.
A Vitamin D3+K2 supplement combines Vitamin D3, which supports calcium absorption from the gut, with Vitamin K2, which may help direct that calcium toward bones rather than soft tissue. The two are commonly paired because Vitamin D increases calcium levels in the blood, and some research suggests K2 supports its proper utilisation. Together they are marketed mainly for bone health support in people with low sun exposure or dietary intake.
For healthy adults, daily Vitamin D3 and K2 co-supplementation at standard doses is safe when following label directions. The ICMR-NIN sets the baseline adult Vitamin D RDA at 600 IU (15 mcg) per day, while no standalone RDA exists for K2. Individuals taking anticoagulant medications like warfarin or those with chronic kidney disease must consult a doctor first, as Vitamin K2 directly interacts with blood-thinning therapies.
It depends on the source and form used. K2 as MK-7 is commonly fermented from natto (a soybean product) and is typically vegetarian, while some older K2 formulations (MK-4) were animal-derived from sources like cheese or egg yolk. Indian brands mostly use the fermented MK-7 form, but this varies by product. Unbox Health independently verifies whether a product's stated Vitamin K2 source and vegetarian claim match its actual tested composition.
Current evidence does not support Vitamin K2 causing kidney stones in healthy individuals at recommended doses; its proposed role is directing calcium toward bone rather than soft tissue, including arteries. People with a history of kidney stones or chronic kidney disease should still consult a doctor before adding any calcium-related supplement, since individual calcium handling varies. This combination has not been shown to reliably prevent or cause kidney stones.
This depends on your existing calcium and bone health status. Vitamin D3 alone addresses deficiency and calcium absorption, the primary concern for most Indians given low sun exposure and limited dietary Vitamin D sources. Adding K2 suits people also taking calcium supplements, though ICMR-NIN has not issued combined dosing guidance for this pairing. Unbox Health independently tests both single and combination products to help compare declared versus actual nutrient content.
The ICMR-NIN recommends 600 IU (15 mcg) of Vitamin D daily for healthy adults, though higher doses are used short-term under medical supervision for diagnosed deficiencies. ICMR-NIN has not established an isolated RDA for Vitamin K2. International bodies like EFSA suggest a total Vitamin K intake of ~70 mcg/day. Always check product labels against your medical requirements before choosing a supplement.
Both Vitamin D3 and K2 are fat-soluble, so taking them with a meal containing some dietary fat, such as milk, ghee or nuts, generally supports better absorption compared to an empty stomach. Tablets, capsules and liquid drops all work through this same principle. Consistency matters more than exact timing, since fat-soluble vitamins are stored in the body rather than needing daily replenishment like water-soluble ones.
There is no single mandated time, but taking Vitamin D3+K2 with your largest or fattiest meal of the day, whether breakfast or dinner, tends to support absorption better than an empty stomach. Some people report mild sleep disruption when taken very late at night, though evidence on this is limited. Sticking to the same time daily helps build a consistent habit more than the specific hour chosen.
Liquid drops allow flexible, smaller dose adjustments and may suit people who have difficulty swallowing tablets, while tablets or capsules offer fixed, consistent dosing that is easier to track daily. Absorption differences between formats are not strongly established for most healthy adults. The right choice depends on convenience and dosing needs rather than one format being clinically superior to the other for most users.
There is no single best option for everyone, since the right product depends on your Vitamin D dose, K2 form (MK-7 versus MK-4) and any existing medical conditions. Rather than choosing based on brand marketing alone, compare the declared dose and form against independently verified data. Unbox Health independently tests Vitamin D3+K2 supplements through NABL-accredited labs to verify whether declared IU and mcg levels match actual tested content.